Improved governance and pre-release safety evaluations needed for biological AI models

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Concerns about biosecurity risks from AI models in biology are escalating. Doni Bloomfield and colleagues advocate for enhanced governance and mandatory pre-release safety evaluations to mitigate these risks. They emphasize the need for national legislation to prevent advanced biological models from contributing to large-scale dangers like pandemics.

While biological AI models offer significant benefits, such as improving drug design and agricultural resilience, they also pose serious risks. The authors highlight the inadequacy of voluntary safety measures and call for standardized evaluations to ensure safety before model release. Policies should focus on high-risk models while allowing scientific exploration of their potential benefits.

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